In summary, sample zone passing through a straight tubing (A) will disperse into a parabolic profile, that can be further modified by:
- coiling the tube (B,b)
- knitting the tube (C,c)
- imprinting the channel in sinusoidal shape (D)
- filling the tube with inert beads (E,e)
The effectiveness of this process can be studied by tracer dye experiments and evaluated means of the thus obtained RTD curves.
Briefly, coiled reactors are most frequently used, being convenient to make. More efficient than coiled are hand knitted (Neue 1982) or perforated tubing mounted reactors. “Single Bead String” reactors are most efficient, but their surface to volume ratio is much larger than of the other reactors and it may lead to adsorption of analytes on stationary beads. Imprinted reactors are half circular in diameter, leaving corners that are slow to wash out. In summary coiled and hand knitted reactors are most practical to use.